Clinical Randomized Comparison of Medetomidine and Xylazine for Isoflurane Balanced Anesthesia in Horses

Clinical Use of a Multivariate Electroencephalogram (Narcotrend) for Assessment of Anesthetic Depth in Horses during Isoflurane–Xylazine Anesthesia

OBJECTIVE To investigate the use of the Narcotrend electroencephalogram (EEG) monitor for the assessment of anesthetic depth in horses undergoing xylazine balanced isoflurane anesthesia. STUDY DESIGN Blinded experimental study. ANIMALS Seven healthy warm-blooded horses, aged 10.6 ± 5.9 years, weighing 535 ± 55 kg. METHODS Horses were anesthetized for a terminal surgical trial with xylazin...

Balanced Anesthesia in Horses

Introduction The phrase “balanced anesthesia” originated from the coadministration of drugs to produce an “ideal” anesthetic state. Today the ideal anesthetic state implies adequate hypnosis, analgesia, muscle relaxation, and relief from stress. The last of these attributes, relief from stress, has been the focus of several investigations conducted in horses in order to determine the magnitude ...

Comparison of α-chloralose, medetomidine and isoflurane anesthesia for functional connectivity mapping in the rat

Functional connectivity measures based upon low-frequency blood-oxygenation-level-dependent functional magnetic resonance imaging (BOLD fMRI) signal fluctuations have become a widely used tool for investigating spontaneous brain activity in humans. Still unknown, however, is the precise relationship between neural activity, the hemodynamic response and fluctuations in the MRI signal. Recent wor...

Preliminary comparison of lidocaine and xylazine as caudal epidural anesthesia for embryo collection in cows

NOTE Surgery Clinical Evaluation of Total Intravenous Anesthesia Using a Combination of Propofol and Medetomidine following Anesthesia Induction with Medetomidine, Guaifenesin and Propofol for Castration in Thoroughbred Horses

Seven Thoroughbred horses were castrated under total intravenous anesthesia (TIVA) using propofol and medetomidine. After premedication with medetomidine (5.0 g/kg, intravenously), anesthesia was induced with guaifenesin (100 mg/kg, intravenously) and propofol (3.0 mg/kg, intravenously) and maintained with constant rate infusions of medetomidine (0.05 g/kg/min) and propofol (0.1 mg/kg/min). Q...